1) Cat. No.: TRC-D242602; 2) Chemical Name: 5'-Deoxy-5'-(methylthio)adenosine-d3; 3) CAS No.: ; 4) Mol. Formula: C11H12D3N5O3S; 5) Mol. Weight: 300.35; 6) Packing Size: 2.5mg / 25mg; 7) Appearence: ; 8) Application Notes: Labelled 5'-Deoxy-5'-(methylthio)adenosine (D242600). 5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN). ; 9) Synonym: 5'-S-(Methyl-d3)-5'-thioadenosine; 5'-(Methylthio-d3)-5'-deoxyadenosine; 5'-(Methylthio-d3)adenosine; 5'-Deoxy(methylthio-d3)adenosine; 5'-S-(Methyl-d3)-5'-thioadenosine; 5'-S-(Methyl-d3)thioadenosine; NSC 335422-d3; Vitamin L2-d3; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-(methyl-d3)-5-thio-β-D-
ribofuranose; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Pegg, A., et al.: Biochem. J., 115, 241 (1969), Olopade, O., et al.: Cancer Res., 53, 2410 (1993), Hartmann, S., et al.: Clin. Chem., 52, 1127 (2006), Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (2010),